In word documents, hyperlink text is a different color than other text and is underlined. Temsirolimus torisel childrens education materials. Safety events were tabulated as maximum severity, and relationship to study drug. It is a derivative and prodrug of sirolimus and is sold as torisel. For outlook, click inside of the body of an item, such as an email message or calendar event. The recommended dose of torisel for advanced renal cell carcinoma is 25 mg infused over a 3060 minute period once a week. Authorization of 3 months may be granted for members prescribed torisel as a single agent. It is usually given by a doctor or nurse in a doctors office or infusion center. Sirolimus or everolimus or temsirolimus and vorinostat in. Cci779 is a potent inhibitor of mtor with ic50 values of 0. Run and import pdf files into the program by clicking add pdf. Its likely that at one point or another, you have been asked to insert or embed a particular pdf image file into a standard microsoft word document. This document contains side effect information about temsirolimus. You may ask how do i insert an entire pdf into a word document.
A hyperlink in a microsoft word document enables readers to jump from the link to a different place in the document, to a different file or website, or to a new email message. How to convert a pdf file into a word document digital. Withdraw precisely the required amount of concentratediluent mixture containing temsirolimus 10 mgml as prepared in step 1 from the vial i. In this article, well teach you how to insert pdf image into word with pdfelement.
It is not difficult to insert pdf into word, but maybe a bit time consuming if you dont have the right tool. Phase ib study of tivozanib av951 in combination with. Studies on shortterm stability of temsirolimus in whole blood andor plasma from. The patient information leaflet pil for torisel 25 mgml concentrate and. Temsirolimus is a cancer medicine that interferes with the growth and spread of cancer cells in the body. Also find the package insert, announcements, resources, and ways to connect with pfizer medical through a variety of channels. Ill cover the following topics in the code samples below. To gain contemporary insights into rcc treatment trends that may. Then click from file on the left side of the dialog box that opens. A new drug application nda for the indication of advanced renal cell. The icon is blank when you insert an object or a file into. Highlights of prescribing information monitor for symptoms. You can either choose to insert pdf into word as the editable content or insert pdf into word as image, lets take a look at the following four solutions. As a first line treatment for renal cell carcinoma, temsirolimus is generally reserved for.
Cci779 is an ester derivative of rapamycin and has improved pharmaceutical properties. If torisel must be given to patients with mild hepatic impairment, reduce the dose of torisel to 15 mgweek. Microsoft wordword 2007, error, adobe, macro, and vb. Find out how to insert and extract one or more pages while working with a pdf file. Everolimus is designed to stop cells from dividing.
Open the word file, the file originally saved in pdf is inserted into the word document successfully. The steps below apply to word 2010, 20, 2016, 2019, and word for office 365. Click or tap where you want to insert the content of the existing document. Torisel medication page for healthcare professionals to search for scientific information on pfizer medications. The torisel vial contains temsirolimus at a concentration of 25 mgml. Management of sorafenib, sunitinib, and temsirolimus toxicity in. Embed pdf in word embed a pdf document into microsoft word. Temsirolimus comes as a solution liquid to be given by infusion slow injection into a vein over 30 to 60 minutes. This video explains how to insert an object in to a document. With word 2007 in the xp operating system it was easy, i just clicked and draged pdf the document into the word document. Torisel, inntemsirolimus european medicines agency. The ndc for torisel is 0008117901 coded as 00008117901 any relevant documentation to support medical necessity package insert, chart or lab notes, letter of medical necessity consult with the payer regarding specific claim and documentation requirements. Read the package leaflet before use and for dilution instructions. Insufficient tumor drug levels and redundant signaling pathways may partly explain.
Using a sterile syringe, slowly inject 5ml of sterile water for injection into the100 mg kadcylavial, or 8 mlof sterile water for injectioninto the 160mg kadcyla vialto yield a solution containing 20 mgml. The finished product, torisel, is a twovial system consisting of a concentrate. How to insert a pdf file into a word document online tech tips. In the occasion that users find some pdf resources instrumental to supplement their paper work, they may want to insert the pdf into word document, especially insert multiple pages pdf files, for editing or other intentions. How to insert an object in to a document in word 2016. This medicine must be given slowly, and the infusion can take up to 60 minutes to complete. Your pdf will now be inserted into excel as an icon. Temsirolimus has demonstrated superiority in terms of os and pfs over ifn. You insert an object or a file into a document, presentation, spreadsheet, or other microsoft office 2003 or microsoft office xp file.
Temsirolimus torisel for kidney cancer chemoexperts. Temsirolimus sensitive stimulation of platelet activity, apoptosis. Some of the dosage forms listed on this page may not apply to the brand name torisel for the consumer. Spread sheet is used as example but same procedure can be followed to insert any other object. Temsirolimus temsuhroleuhmuss is a targeted cancer therapy medication. Embed pdf in word here are the 3 methods that can be used to embed or link a pdf to a microsoft word document. Go to the output file format as following, choose doc. The recommended dose of temsirolimus for advanced rcc is 25 mg. Inspectthe reconstituted solution for particulatesand discoloration. Temsirolimus is used in the treatment of advanced renal cell cancer. Pfizer seeks to stymie sandoz, accords generic torisel. Rearrange individual pages or entire files in the desired order. One of these is the insert pdf to word tool, which enables you to insert a pdf file into a word document in its entirety, or by attaching it as a clickable object. Temsirolimus is given as an injection into the vein intravenous, iv.
Vorinostat is designed to prevent or slow down the growth of cancer cells by blocking proteins. Temsirolimus is designed to slow the growth of kidney cancer cells by inhibiting several mechanisms that the cell uses to grow and survive. Separation and identification of the process impurities in the manufacture of temsirolimus drug viz. Crpplatelet activationdegranulationintegrincytosolic ca. Its an addon for word, and it will let you just click a button, choose the pdf file and configure your options.
Food and drug administration fda in late may 2007, and was also approved by the european medicines agency emea on november 2007. Torisel temsirolimus injection side effects, images. Temsirolimus safety profile and management of toxic effects in. To do this, you use one of the methods in the following examples.
In the absence of crp, the administration of temsirolimus. Outcomes were evaluated by drug class and route of administration. You can insert the content of previouslycreated word documents into a new or different word document. Microsoft word enables users to create and edit documents as they like.
If youre looking to insert the contents of your pdf file into an office file, as opposed to simply inserting the pdf as an attachment, then your best bet is to open that pdf with word 20 or 2016. Please see full prescribing information for torisel temsirolimus. Click object to insert a pdf, image, or another type of nontext file into your word document. Youll notice that once inserted, the pdf takes on an in front of text layout style and hovers above the cells. Pdf files are great, but you might need to make some changes in word. Temsirolimus torisel medical clinical policy bulletins aetna. Torisel is contraindicated in patients with bilirubin 1. Along with its needed effects, temsirolimus the active ingredient contained in torisel may cause some unwanted effects. If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful. There is one other commercial program that is fairly popular which will insert multipage pdf files into a word document without having to worry about converting to an image first called officeexpander. This may stop or slow the growth or spread of cancer cells.
If you want to anchor the pdf to and format with a specific cell, then rightclick the icon. It works by blocking a protein in cells which normally promotes cell growth and division. Place your cursor by clicking on the area where you wish to insert the pdf document. The effects of adding chloroquine, an autophagy inhibitor, to tem were. Embed a pdf document into microsoft word online pc learning. Torisel is indicated for the treatment of advanced renal cell carcinoma. A healthcare provider will give you this injection.
Temsirolimus is designed to block a protein called mtor a protein that is thought to cause cancer cells to grow inside the cancer cell. Temsirolimus is usually given once each week unless your cancer progresses or you have serious side effects from this medicine. Temsirolimus side effects, dosage, interactions drugs everyday health search. Word offers many features that help you present a wide range of different documents, and some can be confusing if youre unfamiliar with them. Temsirolimus codenamed cci779 is an intravenous drug for the treatment of renal cell carcinoma rcc, developed by wyeth pharmaceuticals and approved by the u. In this small phase ib study, tivozanib and temsirolimus were safely combined at. Although adding pictures to text is often thought of more with desktop publishing programs such as microsoft publisher, you can also insert photos into your microsoft word documents. Heres how to convert a pdf file into a word document using a number of. For instructions on dilution and preparation of the medicinal product before administration, see section. Grades 34 aes were reported as drug related in 50% of patients receiving. Realworld treatment patterns and adverse events in metastatic. Comparative study of rapamycin and temsirolimus demonstrates.
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